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Deficiency and excess of groundwater iodine and their health associations
More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708681/ https://www.ncbi.nlm.nih.gov/pubmed/36446773 http://dx.doi.org/10.1038/s41467-022-35042-6 |
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author | Ma, Ruoqi Yan, Mingquan Han, Peng Wang, Ting Li, Bin Zhou, Shungui Zheng, Tong Hu, Yandi Borthwick, Alistair G. L. Zheng, Chunmiao Ni, Jinren |
author_facet | Ma, Ruoqi Yan, Mingquan Han, Peng Wang, Ting Li, Bin Zhou, Shungui Zheng, Tong Hu, Yandi Borthwick, Alistair G. L. Zheng, Chunmiao Ni, Jinren |
author_sort | Ma, Ruoqi |
collection | PubMed |
description | More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic risks relevant to lower iodine more likely occur in the areas of higher altitude, while those associated with high groundwater iodine are concentrated in the areas suffered from transgressions enhanced by land over-use and intensive anthropogenic overexploitation. The potential roles of groundwater iodine species are also explored: iodide might be associated with subclinical hypothyroidism particularly in higher iodine regions, whereas iodate impacts on thyroid risks in presence of universal salt iodization exhibit high uncertainties in lower iodine regions. This implies that accurate iodine supply depending on spatial heterogeneity and dietary iodine structure optimization are highly needed to mitigate thyroid risks in iodine-deficient and -excess areas globally. |
format | Online Article Text |
id | pubmed-9708681 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-97086812022-12-01 Deficiency and excess of groundwater iodine and their health associations Ma, Ruoqi Yan, Mingquan Han, Peng Wang, Ting Li, Bin Zhou, Shungui Zheng, Tong Hu, Yandi Borthwick, Alistair G. L. Zheng, Chunmiao Ni, Jinren Nat Commun Article More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic risks relevant to lower iodine more likely occur in the areas of higher altitude, while those associated with high groundwater iodine are concentrated in the areas suffered from transgressions enhanced by land over-use and intensive anthropogenic overexploitation. The potential roles of groundwater iodine species are also explored: iodide might be associated with subclinical hypothyroidism particularly in higher iodine regions, whereas iodate impacts on thyroid risks in presence of universal salt iodization exhibit high uncertainties in lower iodine regions. This implies that accurate iodine supply depending on spatial heterogeneity and dietary iodine structure optimization are highly needed to mitigate thyroid risks in iodine-deficient and -excess areas globally. Nature Publishing Group UK 2022-11-29 /pmc/articles/PMC9708681/ /pubmed/36446773 http://dx.doi.org/10.1038/s41467-022-35042-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Ma, Ruoqi Yan, Mingquan Han, Peng Wang, Ting Li, Bin Zhou, Shungui Zheng, Tong Hu, Yandi Borthwick, Alistair G. L. Zheng, Chunmiao Ni, Jinren Deficiency and excess of groundwater iodine and their health associations |
title | Deficiency and excess of groundwater iodine and their health associations |
title_full | Deficiency and excess of groundwater iodine and their health associations |
title_fullStr | Deficiency and excess of groundwater iodine and their health associations |
title_full_unstemmed | Deficiency and excess of groundwater iodine and their health associations |
title_short | Deficiency and excess of groundwater iodine and their health associations |
title_sort | deficiency and excess of groundwater iodine and their health associations |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708681/ https://www.ncbi.nlm.nih.gov/pubmed/36446773 http://dx.doi.org/10.1038/s41467-022-35042-6 |
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