Cargando…

Deficiency and excess of groundwater iodine and their health associations

More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Ruoqi, Yan, Mingquan, Han, Peng, Wang, Ting, Li, Bin, Zhou, Shungui, Zheng, Tong, Hu, Yandi, Borthwick, Alistair G. L., Zheng, Chunmiao, Ni, Jinren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708681/
https://www.ncbi.nlm.nih.gov/pubmed/36446773
http://dx.doi.org/10.1038/s41467-022-35042-6
_version_ 1784840989525934080
author Ma, Ruoqi
Yan, Mingquan
Han, Peng
Wang, Ting
Li, Bin
Zhou, Shungui
Zheng, Tong
Hu, Yandi
Borthwick, Alistair G. L.
Zheng, Chunmiao
Ni, Jinren
author_facet Ma, Ruoqi
Yan, Mingquan
Han, Peng
Wang, Ting
Li, Bin
Zhou, Shungui
Zheng, Tong
Hu, Yandi
Borthwick, Alistair G. L.
Zheng, Chunmiao
Ni, Jinren
author_sort Ma, Ruoqi
collection PubMed
description More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic risks relevant to lower iodine more likely occur in the areas of higher altitude, while those associated with high groundwater iodine are concentrated in the areas suffered from transgressions enhanced by land over-use and intensive anthropogenic overexploitation. The potential roles of groundwater iodine species are also explored: iodide might be associated with subclinical hypothyroidism particularly in higher iodine regions, whereas iodate impacts on thyroid risks in presence of universal salt iodization exhibit high uncertainties in lower iodine regions. This implies that accurate iodine supply depending on spatial heterogeneity and dietary iodine structure optimization are highly needed to mitigate thyroid risks in iodine-deficient and -excess areas globally.
format Online
Article
Text
id pubmed-9708681
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-97086812022-12-01 Deficiency and excess of groundwater iodine and their health associations Ma, Ruoqi Yan, Mingquan Han, Peng Wang, Ting Li, Bin Zhou, Shungui Zheng, Tong Hu, Yandi Borthwick, Alistair G. L. Zheng, Chunmiao Ni, Jinren Nat Commun Article More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic risks relevant to lower iodine more likely occur in the areas of higher altitude, while those associated with high groundwater iodine are concentrated in the areas suffered from transgressions enhanced by land over-use and intensive anthropogenic overexploitation. The potential roles of groundwater iodine species are also explored: iodide might be associated with subclinical hypothyroidism particularly in higher iodine regions, whereas iodate impacts on thyroid risks in presence of universal salt iodization exhibit high uncertainties in lower iodine regions. This implies that accurate iodine supply depending on spatial heterogeneity and dietary iodine structure optimization are highly needed to mitigate thyroid risks in iodine-deficient and -excess areas globally. Nature Publishing Group UK 2022-11-29 /pmc/articles/PMC9708681/ /pubmed/36446773 http://dx.doi.org/10.1038/s41467-022-35042-6 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Ma, Ruoqi
Yan, Mingquan
Han, Peng
Wang, Ting
Li, Bin
Zhou, Shungui
Zheng, Tong
Hu, Yandi
Borthwick, Alistair G. L.
Zheng, Chunmiao
Ni, Jinren
Deficiency and excess of groundwater iodine and their health associations
title Deficiency and excess of groundwater iodine and their health associations
title_full Deficiency and excess of groundwater iodine and their health associations
title_fullStr Deficiency and excess of groundwater iodine and their health associations
title_full_unstemmed Deficiency and excess of groundwater iodine and their health associations
title_short Deficiency and excess of groundwater iodine and their health associations
title_sort deficiency and excess of groundwater iodine and their health associations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708681/
https://www.ncbi.nlm.nih.gov/pubmed/36446773
http://dx.doi.org/10.1038/s41467-022-35042-6
work_keys_str_mv AT maruoqi deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT yanmingquan deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT hanpeng deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT wangting deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT libin deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT zhoushungui deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT zhengtong deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT huyandi deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT borthwickalistairgl deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT zhengchunmiao deficiencyandexcessofgroundwateriodineandtheirhealthassociations
AT nijinren deficiencyandexcessofgroundwateriodineandtheirhealthassociations