Cargando…

Protective effects of safranal on diabetic retinopathy in human microvascular endothelial cells and related pathways analyzed with transcriptome sequencing

AIM: To determine the effect of safranal on diabetic retinopathy in vitro and its possible mechanisms. METHODS: We used human retinal microvascular endothelial cells (HRMECs) to test the influence of safranal in vitro. High glucose damage was established and an safranal was tested at various concent...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiao, Qin, Sun, Yao-Yao, Lu, Zhan-Jun, Li, Shan-shan, Su, Riguga, Chen, Wen-Lin, Ran, Lin-Lin, Zhang, Surina, Deng, Kaixin, Yu, Wen-Zhen, Chen, Wenqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708741/ https://www.ncbi.nlm.nih.gov/pubmed/36465659 http://dx.doi.org/10.3389/fendo.2022.945446

Ejemplares similares

Endothelial Dysfunction in Diabetic Retinopathy
por: Gui, Fu, et al.
Publicado: (2020)

The legacy of Jeremy Safran
por: Lingiardi, Vittorio, et al.
Publicado: (2019)

Endothelial Progenitor Cells in Diabetic Retinopathy
por: Lois, Noemi, et al.
Publicado: (2014)

The Impaired Bioenergetics of Diabetic Cardiac Microvascular Endothelial Cells
por: Zhang, Haitao, et al.
Publicado: (2021)

Transcriptional Analysis of Sepsis-Induced Activation and Damage of the Adrenal Endothelial Microvascular Cells
por: Chen, Lan-Sun, et al.
Publicado: (2020)

Association Between Obesity and Microvascular Diseases in Patients With Type 2 Diabetes Mellitus
por: Gao, Shan, et al.
Publicado: (2021)

Mechanistic Pathogenesis of Endothelial Dysfunction in Diabetic Nephropathy and Retinopathy
por: Yang, Jing, et al.
Publicado: (2022)

The ideal treatment timing for diabetic retinopathy: the molecular pathological mechanisms underlying early-stage diabetic retinopathy are a matter of concern
por: Sun, Wen-Jie, et al.
Publicado: (2023)

The role of protein kinase C in diabetic microvascular complications
por: Pan, Deng, et al.
Publicado: (2022)

Affinity-based target deconvolution of safranal
por: Hosseinzadeh, Hossein, et al.
Publicado: (2013)

Jeremy Safran: a hero’s journey
por: Horvath, Adam Otto
Publicado: (2019)

Pharmacological effects of Safranal: An updated review
por: Esmaealzadeh, Danial, et al.
Publicado: (2023)

The Relaxant Activity of Safranal in Isolated Rat Aortas is Mediated Predominantly via an Endothelium-Independent Mechanism: -Vasodilatory mechanism of safranal-
por: Razavi, Bibi Marjan, et al.
Publicado: (2016)

Is preclinical diabetic retinopathy in diabetic nephropathy individuals more severe?
por: Yao, Hongyan, et al.
Publicado: (2023)

Ruptures, repairs, and reflections: contributions of Jeremy Safran
por: Samstag, Lisa Wallner, et al.
Publicado: (2019)

Macrophage/microglia polarization for the treatment of diabetic retinopathy
por: Yao, Yujia, et al.
Publicado: (2023)

Diabetic retinopathy risk prediction in patients with type 2 diabetes mellitus using a nomogram model
por: Wang, Qian, et al.
Publicado: (2022)

Novel risk score model for non-proliferative diabetic retinopathy based on untargeted metabolomics of venous blood
por: Wang, Xinyu, et al.
Publicado: (2023)

Meta-Analysis of Relationship of Sleep Quality and Duration With Risk of Diabetic Retinopathy
por: Zheng, Zhenzhen, et al.
Publicado: (2022)

Advances in targeted retinal photocoagulation in the treatment of diabetic retinopathy
por: Lin, Zichun, et al.
Publicado: (2023)

Research progress on exosomes/microRNAs in the treatment of diabetic retinopathy
por: Niu, Si-ru, et al.
Publicado: (2022)

Chemerin promotes microangiopathy in diabetic retinopathy via activation of ChemR23 in rat primary microvascular endothelial cells
por: Jun, Li, et al.
Publicado: (2021)

Role of Lipid Indices in the Assessment of Microvascular Risk in Type 2 Diabetic Retinopathy Patients
por: Namitha, Devegowda, et al.
Publicado: (2022)

Associations of Serum Cathepsin K and Polymorphisms in CTSK Gene With Bone Mineral Density and Bone Metabolism Markers in Postmenopausal Chinese Women
por: Gao, Li-hong, et al.
Publicado: (2020)

Ferroptosis: new insight into the mechanisms of diabetic nephropathy and retinopathy
por: Li, Luxin, et al.
Publicado: (2023)

Exploring the Immune Infiltration Landscape and M2 Macrophage-Related Biomarkers of Proliferative Diabetic Retinopathy
por: Meng, Zhishang, et al.
Publicado: (2022)

Anti-tumor activity of safranal against neuroblastoma cells
por: Samarghandian, Saeed, et al.
Publicado: (2014)

Safranal as a safe compound to mice immune system
por: Riahi-Zanjani, Bamdad, et al.
Publicado: (2015)

The application of sudoscan for screening microvascular complications in patients with type 2 diabetes
por: Lin, Kun, et al.
Publicado: (2022)

Association between adipocytokines and diabetic retinopathy: a systematic review and meta-analysis
por: Jiang, Yanhua, et al.
Publicado: (2023)

Specific alterations of gut microbiota in diabetic microvascular complications: A systematic review and meta-analysis
por: Hong, Jinni, et al.
Publicado: (2022)

LGR4 Gene Polymorphisms Are Associated With Bone and Obesity Phenotypes in Chinese Female Nuclear Families
por: Shi, Su-qin, et al.
Publicado: (2021)

The Relationship Between Circulating Growth Differentiation Factor 15 Levels and Diabetic Retinopathy in Patients With Type 2 Diabetes
por: Niu, Yixin, et al.
Publicado: (2021)

Porphyromonas gingivalis outer membrane vesicles exacerbate retinal microvascular endothelial cell dysfunction in diabetic retinopathy
por: Huang, Shengyuan, et al.
Publicado: (2023)

Klotho’s impact on diabetic nephropathy and its emerging connection to diabetic retinopathy
por: Tang, Anqi, et al.
Publicado: (2023)

The relationship between renal function and surgical outcomes of patients with proliferative diabetic retinopathy
por: Liu, Jin, et al.
Publicado: (2022)

Risk of diabetic retinopathy and retinal neurodegeneration in individuals with type 2 diabetes: Beichen Eye Study
por: Yang, Zhengwei, et al.
Publicado: (2023)

The role of aldosterone in the pathogenesis of diabetic retinopathy
por: Liu, Kangcheng, et al.
Publicado: (2023)

Correlation between diabetic retinopathy and diabetic nephropathy: a two-sample Mendelian randomization study
por: Fang, Jiaxi, et al.
Publicado: (2023)

Long-Term Oral Administration of Salidroside Alleviates Diabetic Retinopathy in db/db Mice
por: Yao, Fei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c3goqfl1rngjecis5j1lp8ci5r