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FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells
The specification, characterization, and fate of alveolar type 1 and type 2 (AT1 and AT2) progenitors during embryonic lung development are poorly defined. Current models of distal epithelial lineage formation fail to capture the heterogeneity and dynamic contribution of progenitor pools present dur...
Autores principales: | Jones, Matthew R., Lingampally, Arun, Ahmadvand, Negah, Chong, Lei, Wu, Jin, Wilhem, Jochen, Vazquez-Armendariz, Ana Ivonne, Ansari, Meshal, Herold, Susanne, Ornitz, David M., Schiller, Herbert B., Chao, Cho-Ming, Zhang, Jin-San, Carraro, Gianni, Bellusci, Saverio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708820/ https://www.ncbi.nlm.nih.gov/pubmed/36445537 http://dx.doi.org/10.1007/s00018-022-04626-2 |
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