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The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy
OBJECTIVE: The purpose of the study was to evaluate the predictive value of prognostic nutritional index (PNI) on early complications (within 30-day) after robot-assisted radical cystectomy (RARC) and urinary diversion. PATIENTS AND METHODS: Patients underwent RARC and urinary diversion between Nove...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708885/ https://www.ncbi.nlm.nih.gov/pubmed/36468076 http://dx.doi.org/10.3389/fsurg.2022.985292 |
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author | Wang, Yiduo Lu, Xun Gao, Yue Liu, Ning Jiang, Hua Chen, Shuqiu Chen, Ming |
author_facet | Wang, Yiduo Lu, Xun Gao, Yue Liu, Ning Jiang, Hua Chen, Shuqiu Chen, Ming |
author_sort | Wang, Yiduo |
collection | PubMed |
description | OBJECTIVE: The purpose of the study was to evaluate the predictive value of prognostic nutritional index (PNI) on early complications (within 30-day) after robot-assisted radical cystectomy (RARC) and urinary diversion. PATIENTS AND METHODS: Patients underwent RARC and urinary diversion between November 2018 and December 2021 in our centre were screened in this retrospective study. Baseline characteristics and perioperative data were recorded. Early complications after surgery were classified according to Clavien-Dindo system. Univariate and multivariate logistic analysis were performed to decide the potential factors associated with post-RARC complications. The receiver operating characteristic (ROC) curve was conducted to determine the predictive value of PNI on early overall and major complications after RARC. RESULTS: Overall 139 men and 13 women with a median age of 69 years and mean BMI of 24.4 kg/m(2) were included in this study. As for urinary diversion, most patients (n = 111, 73%) received cutaneous ureterostomy, 36 patients (23.7%) underwent orthotopic neobladder and 5 patients (3.3%) received ileal conduit. The incidence of postoperative complication rate was 44.7%, which included 82.2% minor complications and 17.8% major complications. Further univariate and multivariate logistic analyses demonstrated that hypertension (OR = 2.96, 95% CI: 1.24–7.07, P = 0.015), PNI (OR = 0.73, 95% CI: 0.62–0.86, P < 0.001), and CCI (OR = 1.44, 95% CI: 1.01–2.06, P = 0.047) were independent risk factors of early complications after RARC. Moreover, PNI (OR = 0.72, 95% CI: 0.60–0.86, P < 0.001) was also the predictor of major complications after RARC. The ROC curve demonstrated that PNI (AUC = 0.829; AUC = 0.840) has a great predictive value in early overall and major complications after RARC. CONCLUSION: PNI can be an early alert for RARC patients thus aiding in closer monitoring and postoperative management. |
format | Online Article Text |
id | pubmed-9708885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97088852022-12-01 The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy Wang, Yiduo Lu, Xun Gao, Yue Liu, Ning Jiang, Hua Chen, Shuqiu Chen, Ming Front Surg Surgery OBJECTIVE: The purpose of the study was to evaluate the predictive value of prognostic nutritional index (PNI) on early complications (within 30-day) after robot-assisted radical cystectomy (RARC) and urinary diversion. PATIENTS AND METHODS: Patients underwent RARC and urinary diversion between November 2018 and December 2021 in our centre were screened in this retrospective study. Baseline characteristics and perioperative data were recorded. Early complications after surgery were classified according to Clavien-Dindo system. Univariate and multivariate logistic analysis were performed to decide the potential factors associated with post-RARC complications. The receiver operating characteristic (ROC) curve was conducted to determine the predictive value of PNI on early overall and major complications after RARC. RESULTS: Overall 139 men and 13 women with a median age of 69 years and mean BMI of 24.4 kg/m(2) were included in this study. As for urinary diversion, most patients (n = 111, 73%) received cutaneous ureterostomy, 36 patients (23.7%) underwent orthotopic neobladder and 5 patients (3.3%) received ileal conduit. The incidence of postoperative complication rate was 44.7%, which included 82.2% minor complications and 17.8% major complications. Further univariate and multivariate logistic analyses demonstrated that hypertension (OR = 2.96, 95% CI: 1.24–7.07, P = 0.015), PNI (OR = 0.73, 95% CI: 0.62–0.86, P < 0.001), and CCI (OR = 1.44, 95% CI: 1.01–2.06, P = 0.047) were independent risk factors of early complications after RARC. Moreover, PNI (OR = 0.72, 95% CI: 0.60–0.86, P < 0.001) was also the predictor of major complications after RARC. The ROC curve demonstrated that PNI (AUC = 0.829; AUC = 0.840) has a great predictive value in early overall and major complications after RARC. CONCLUSION: PNI can be an early alert for RARC patients thus aiding in closer monitoring and postoperative management. Frontiers Media S.A. 2022-11-16 /pmc/articles/PMC9708885/ /pubmed/36468076 http://dx.doi.org/10.3389/fsurg.2022.985292 Text en © 2022 Wang, Lu, Gao, Liu, Jiang, Chen and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Wang, Yiduo Lu, Xun Gao, Yue Liu, Ning Jiang, Hua Chen, Shuqiu Chen, Ming The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy |
title | The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy |
title_full | The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy |
title_fullStr | The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy |
title_full_unstemmed | The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy |
title_short | The predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy |
title_sort | predictive value of prognostic nutritional index on early complications after robot-assisted radical cystectomy |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708885/ https://www.ncbi.nlm.nih.gov/pubmed/36468076 http://dx.doi.org/10.3389/fsurg.2022.985292 |
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