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Intracellular VHHs to monitor and modulate GPCR signaling

Single-domain antibody fragments, also known as VHHs or nanobodies, have opened promising avenues in therapeutics and in exploration of intracellular processes. Because of their unique structural properties, they can reach cryptic regions in their cognate antigen. Intracellular VHHs/antibodies prima...

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Detalles Bibliográficos
Autores principales: Raynaud, Pauline, Gauthier, Camille, Jugnarain, Vinesh, Jean-Alphonse, Frédéric, Reiter, Eric, Bruneau, Gilles, Crépieux, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708903/
https://www.ncbi.nlm.nih.gov/pubmed/36465650
http://dx.doi.org/10.3389/fendo.2022.1048601