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LncRNA IL21‐AS1 interacts with hnRNPU protein to promote IL21 overexpression and aberrant differentiation of Tfh cells in systemic lupus erythematosus

BACKGROUND: The aberrant differentiation of T follicular helper (Tfh) cells plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). However, the mechanism of regulating Tfh cells differentiation remains unclear. Long noncoding RNAs (lncRNAs) act as important regulators in...

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Detalles Bibliográficos
Autores principales: Liu, Limin, Hu, Longyuan, Long, Haojun, Zheng, Meiling, Hu, Zhi, He, Ye, Gao, Xiaofei, Du, Pei, Zhao, Hongjun, Yu, Di, Lu, Qianjin, Zhao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708910/
https://www.ncbi.nlm.nih.gov/pubmed/36447054
http://dx.doi.org/10.1002/ctm2.1117