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Examination of generational impacts of adolescent chemotherapy: Ifosfamide and potential for epigenetic transgenerational inheritance

The current study was designed to use a rodent model to determine if exposure to the chemotherapy drug ifosfamide during puberty can induce altered phenotypes and disease in the grand-offspring of exposed individuals through epigenetic transgenerational inheritance. Pathologies such as delayed puber...

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Detalles Bibliográficos
Autores principales: Thompson, Ryan P., Beck, Daniel, Nilsson, Eric, Ben Maamar, Millissia, Shnorhavorian, Margarett, Skinner, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708925/
https://www.ncbi.nlm.nih.gov/pubmed/36465105
http://dx.doi.org/10.1016/j.isci.2022.105570