Transcriptomic comparison of primary human lung cells with lung tissue samples and the human A549 lung cell line highlights cell type specific responses during infections with influenza A virus

Influenza A virus (IAV) causes pandemics and annual epidemics of severe respiratory infections. A better understanding of the molecular regulation in tissue and cells upon IAV infection is needed to thoroughly understand pathogenesis. We analyzed IAV replication and gene expression induced by IAV st...

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Detalles Bibliográficos
Autores principales: Bertrams, Wilhelm, Hönzke, Katja, Obermayer, Benedikt, Tönnies, Mario, Bauer, Torsten T., Schneider, Paul, Neudecker, Jens, Rückert, Jens C., Stiewe, Thorsten, Nist, Andrea, Eggeling, Stephan, Suttorp, Norbert, Wolff, Thorsten, Hippenstiel, Stefan, Schmeck, Bernd, Hocke, Andreas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709075/
https://www.ncbi.nlm.nih.gov/pubmed/36446841
http://dx.doi.org/10.1038/s41598-022-24792-4

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