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Inverted genomic regions between reference genome builds in humans impact imputation accuracy and decrease the power of association testing
Over the last two decades, the human reference genome has undergone multiple updates as we complete a linear representation of our genome. Two versions of human references are currently used in the biomedical literature, GRCh37/hg19 and GRCh38. Conversions between these versions are critical for qua...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709082/ https://www.ncbi.nlm.nih.gov/pubmed/36465187 http://dx.doi.org/10.1016/j.xhgg.2022.100159 |