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Tryptophan was metabolized into beneficial metabolites against coronary heart disease or prevented from producing harmful metabolites by the in vitro drug screening model based on Clostridium sporogenes

In our previous study of 2,130 Chinese patients with coronary heart disease (CHD), we found that tryptophan (TRP) metabolites contributed to elevated risks of death. Many TRP-derived metabolites require the participation of intestinal bacteria to produce, and they play an important role in the patho...

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Detalles Bibliográficos
Autores principales: Tian, XiaoXue, Wu, Yuanyuan, Duan, Cheng, Zhou, Xiaohong, Li, Yong, Zheng, Jiabin, Lai, Weihua, Zhang, Shuyao, Cao, Lixiang, Zhong, Shilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709117/
https://www.ncbi.nlm.nih.gov/pubmed/36466649
http://dx.doi.org/10.3389/fmicb.2022.1013973