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Mitochondria-originated redox signalling regulates KLF-1 to promote longevity in Caenorhabditis elegans
Alternations of redox metabolism have been associated with the extension of lifespan in roundworm Caenorhabditis elegans, caused by moderate mitochondrial dysfunction, although the underlying signalling cascades are largely unknown. Previously, we identified transcriptional factor Krüppel-like facto...
Autores principales: | Hermeling, Johannes CW, Herholz, Marija, Baumann, Linda, Cores, Estela Cepeda, Zečić, Aleksandra, Hoppe, Thorsten, Riemer, Jan, Trifunovic, Aleksandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709155/ https://www.ncbi.nlm.nih.gov/pubmed/36442394 http://dx.doi.org/10.1016/j.redox.2022.102533 |
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