CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma

Adult T-cell leukemia/lymphoma (ATL) is caused by human T-cell leukemia virus type 1 (HTLV-1). In addition to HTLV-1 bZIP factor (HBZ), a leukemogenic antisense transcript of HTLV-1, abnormalities of genes involved in TCR-NF-κB signaling, such as CARD11, are detected in about 90% of patients. Utiliz...

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Detalles Bibliográficos
Autores principales: Kameda, Takuro, Shide, Kotaro, Kamiunten, Ayako, Kogure, Yasunori, Morishita, Daisuke, Koya, Junji, Tahira, Yuki, Akizuki, Keiichi, Yokomizo-Nakano, Takako, Kubota, Sho, Marutsuka, Kosuke, Sekine, Masaaki, Hidaka, Tomonori, Kubuki, Yoko, Kitai, Yuichi, Matsuda, Tadashi, Yoda, Akinori, Ohshima, Takayuki, Sugiyama, Midori, Sashida, Goro, Kataoka, Keisuke, Ogawa, Seishi, Shimoda, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709164/
https://www.ncbi.nlm.nih.gov/pubmed/36446869
http://dx.doi.org/10.1038/s42003-022-04284-x

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