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PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis

The tumor suppressor protein p53 suppresses cancer by regulating processes such as apoptosis, cell cycle arrest, senescence, and ferroptosis, which is an iron-mediated and lipid peroxide–induced cell death pathway. Whereas numerous p53 target genes have been identified, only a few appear to be criti...

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Detalles Bibliográficos
Autores principales:	Gnanapradeepan, Keerthana, Indeglia, Alexandra, Stieg, David C., Clarke, Nicole, Shao, Chunlei, Dougherty, James F., Murali, Nivitha, Murphy, Maureen E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709240/ https://www.ncbi.nlm.nih.gov/pubmed/36309086 http://dx.doi.org/10.1016/j.jbc.2022.102637

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