Functional properties of circular RNAs and research progress in gastric cancer

Circular RNAs (circRNAs) are a class of closed circular non-coding RNAs widely exist in eukaryotes, with high stability and species conservation. A large number of studies have shown that circRNAs are abnormally expressed in various tumor tissues, and are abundant in plasma with long half-life and h...

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Autores principales: Ding, Ping’an, Liu, Pengpeng, Wu, Haotian, Yang, Peigang, Tian, Yuan, Zhao, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709261/
https://www.ncbi.nlm.nih.gov/pubmed/36465346
http://dx.doi.org/10.3389/fonc.2022.954637
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author Ding, Ping’an
Liu, Pengpeng
Wu, Haotian
Yang, Peigang
Tian, Yuan
Zhao, Qun
author_facet Ding, Ping’an
Liu, Pengpeng
Wu, Haotian
Yang, Peigang
Tian, Yuan
Zhao, Qun
author_sort Ding, Ping’an
collection PubMed
description Circular RNAs (circRNAs) are a class of closed circular non-coding RNAs widely exist in eukaryotes, with high stability and species conservation. A large number of studies have shown that circRNAs are abnormally expressed in various tumor tissues, and are abundant in plasma with long half-life and high specificity, which may be served as potential tumor biomarkers for early diagnosis, treatment and prognosis of malignant tumors. However, the role of circRNAs is still poorly understood in gastric cancer. This article reviews the research progress of circRNAs in gastric cancer in recent years so as to explore the relationship between circRNAs and the occurrence and the development of gastric cancer, and provide new ideas for the diagnosis and treatment of gastric cancer.
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spelling pubmed-97092612022-12-01 Functional properties of circular RNAs and research progress in gastric cancer Ding, Ping’an Liu, Pengpeng Wu, Haotian Yang, Peigang Tian, Yuan Zhao, Qun Front Oncol Oncology Circular RNAs (circRNAs) are a class of closed circular non-coding RNAs widely exist in eukaryotes, with high stability and species conservation. A large number of studies have shown that circRNAs are abnormally expressed in various tumor tissues, and are abundant in plasma with long half-life and high specificity, which may be served as potential tumor biomarkers for early diagnosis, treatment and prognosis of malignant tumors. However, the role of circRNAs is still poorly understood in gastric cancer. This article reviews the research progress of circRNAs in gastric cancer in recent years so as to explore the relationship between circRNAs and the occurrence and the development of gastric cancer, and provide new ideas for the diagnosis and treatment of gastric cancer. Frontiers Media S.A. 2022-11-16 /pmc/articles/PMC9709261/ /pubmed/36465346 http://dx.doi.org/10.3389/fonc.2022.954637 Text en Copyright © 2022 Ding, Liu, Wu, Yang, Tian and Zhao https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Ding, Ping’an
Liu, Pengpeng
Wu, Haotian
Yang, Peigang
Tian, Yuan
Zhao, Qun
Functional properties of circular RNAs and research progress in gastric cancer
title Functional properties of circular RNAs and research progress in gastric cancer
title_full Functional properties of circular RNAs and research progress in gastric cancer
title_fullStr Functional properties of circular RNAs and research progress in gastric cancer
title_full_unstemmed Functional properties of circular RNAs and research progress in gastric cancer
title_short Functional properties of circular RNAs and research progress in gastric cancer
title_sort functional properties of circular rnas and research progress in gastric cancer
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709261/
https://www.ncbi.nlm.nih.gov/pubmed/36465346
http://dx.doi.org/10.3389/fonc.2022.954637
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