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Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection
The twin pandemics of opioid abuse and HIV infection can have devastating effects on physiological systems, including on the brain. Our previous work found that morphine increased the viral reservoir in the brains of treated SIV-infected macaques. In this study, we investigated the interaction of mo...
Autores principales: | Fox, Howard S., Niu, Meng, Morsey, Brenda M., Lamberty, Benjamin G., Emanuel, Katy, Periyasamy, Palsamy, Callen, Shannon, Acharya, Arpan, Kubik, Gregory, Eudy, James, Guda, Chittibabu, Dyavar, Shetty Ravi, Fletcher, Courtney V., Byrareddy, Siddappa N., Buch, Shilpa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709286/ https://www.ncbi.nlm.nih.gov/pubmed/36466814 http://dx.doi.org/10.3389/fimmu.2022.1012884 |
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