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Morphine suppresses peripheral responses and transforms brain myeloid gene expression to favor neuropathogenesis in SIV infection

The twin pandemics of opioid abuse and HIV infection can have devastating effects on physiological systems, including on the brain. Our previous work found that morphine increased the viral reservoir in the brains of treated SIV-infected macaques. In this study, we investigated the interaction of mo...

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Detalles Bibliográficos
Autores principales: Fox, Howard S., Niu, Meng, Morsey, Brenda M., Lamberty, Benjamin G., Emanuel, Katy, Periyasamy, Palsamy, Callen, Shannon, Acharya, Arpan, Kubik, Gregory, Eudy, James, Guda, Chittibabu, Dyavar, Shetty Ravi, Fletcher, Courtney V., Byrareddy, Siddappa N., Buch, Shilpa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709286/
https://www.ncbi.nlm.nih.gov/pubmed/36466814
http://dx.doi.org/10.3389/fimmu.2022.1012884

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