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Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies
Toxin A (TcdA) and toxin B (TcdB) are two key virulence factors secreted by Clostridioides difficile, which is listed as an urgent threat by the CDC. These two large homologous exotoxins are mainly responsible for diseases associated with C. difficile infection (CDI) with symptoms ranging from diarr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709291/ https://www.ncbi.nlm.nih.gov/pubmed/36466927 http://dx.doi.org/10.3389/fimmu.2022.978858 |