Reprogramming of T cell‐derived small extracellular vesicles using IL2 surface engineering induces potent anti‐cancer effects through miRNA delivery

T cell‐derived small extracellular vesicles (sEVs) exhibit anti‐cancer effects. However, their anti‐cancer potential should be reinforced to enhance clinical applicability. Herein, we generated interleukin‐2‐tethered sEVs (IL2‐sEVs) from engineered Jurkat T cells expressing IL2 at the plasma membran...

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Detalles Bibliográficos
Autores principales: Jung, Dokyung, Shin, Sanghee, Kang, Sung‐Min, Jung, Inseong, Ryu, Suyeon, Noh, Soojeong, Choi, Sung‐Jin, Jeong, Jongwon, Lee, Beom Yong, Kim, Kwang‐Soo, Kim, Christine Seulki, Yoon, Jong Hyuk, Lee, Chan‐Hyeong, Bucher, Felicitas, Kim, Yong‐Nyun, Im, Sin‐Hyeog, Song, Byoung‐Joon, Yea, Kyungmoo, Baek, Moon‐Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709340/
https://www.ncbi.nlm.nih.gov/pubmed/36447429
http://dx.doi.org/10.1002/jev2.12287

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