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Laryngeal Lymphoma in a Child – Case Report and Review of Literature

INTRODUCTION: Head and neck is the second most common region for lymphomas. Extranodal lymphomas of the larynx are rare in the pediatric population. Non Hodgkin Lymphoma (NHL) of the larynx is common in the supraglottic region as its rich in lymphoid tissue. They may present with dysphagia, dysphoni...

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Autores principales: Ayyaswamy, Anupriya, Saravanam, Prasanna Kumar, Latha, Sneha, Sundaram, Sandhya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709388/
https://www.ncbi.nlm.nih.gov/pubmed/36474489
http://dx.doi.org/10.22038/IJORL.2022.57663.2984
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author Ayyaswamy, Anupriya
Saravanam, Prasanna Kumar
Latha, Sneha
Sundaram, Sandhya
author_facet Ayyaswamy, Anupriya
Saravanam, Prasanna Kumar
Latha, Sneha
Sundaram, Sandhya
author_sort Ayyaswamy, Anupriya
collection PubMed
description INTRODUCTION: Head and neck is the second most common region for lymphomas. Extranodal lymphomas of the larynx are rare in the pediatric population. Non Hodgkin Lymphoma (NHL) of the larynx is common in the supraglottic region as its rich in lymphoid tissue. They may present with dysphagia, dysphonia, snoring and progressive respiratory distress. Early visualization of the larynx is essential in such cases for appropriate diagnosis to improve the survival rates. CASE REPORT: We present a case of 9 year old boy who presented with a change in voice, snoring and feeding difficulties for one year. Video laryngoscopy revealed globular mass arising from the epiglottis. He underwent excision biopsy and by immunohistochemistry was diagnosed to have diffuse large B cell lymphoma. He was treated with chemotherapy and the child is clinically well in the follow-up, 1 year after the completion of therapy. CONCLUSIONS: Although primary lymphomas of the larynx in children are rare, a high index of clinical suspicion is warranted to avoid diagnostic delays to initiate appropriate management to have better outcomes.
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spelling pubmed-97093882022-12-05 Laryngeal Lymphoma in a Child – Case Report and Review of Literature Ayyaswamy, Anupriya Saravanam, Prasanna Kumar Latha, Sneha Sundaram, Sandhya Iran J Otorhinolaryngol Case Report INTRODUCTION: Head and neck is the second most common region for lymphomas. Extranodal lymphomas of the larynx are rare in the pediatric population. Non Hodgkin Lymphoma (NHL) of the larynx is common in the supraglottic region as its rich in lymphoid tissue. They may present with dysphagia, dysphonia, snoring and progressive respiratory distress. Early visualization of the larynx is essential in such cases for appropriate diagnosis to improve the survival rates. CASE REPORT: We present a case of 9 year old boy who presented with a change in voice, snoring and feeding difficulties for one year. Video laryngoscopy revealed globular mass arising from the epiglottis. He underwent excision biopsy and by immunohistochemistry was diagnosed to have diffuse large B cell lymphoma. He was treated with chemotherapy and the child is clinically well in the follow-up, 1 year after the completion of therapy. CONCLUSIONS: Although primary lymphomas of the larynx in children are rare, a high index of clinical suspicion is warranted to avoid diagnostic delays to initiate appropriate management to have better outcomes. Mashhad University of Medical Sciences 2022-11 /pmc/articles/PMC9709388/ /pubmed/36474489 http://dx.doi.org/10.22038/IJORL.2022.57663.2984 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ayyaswamy, Anupriya
Saravanam, Prasanna Kumar
Latha, Sneha
Sundaram, Sandhya
Laryngeal Lymphoma in a Child – Case Report and Review of Literature
title Laryngeal Lymphoma in a Child – Case Report and Review of Literature
title_full Laryngeal Lymphoma in a Child – Case Report and Review of Literature
title_fullStr Laryngeal Lymphoma in a Child – Case Report and Review of Literature
title_full_unstemmed Laryngeal Lymphoma in a Child – Case Report and Review of Literature
title_short Laryngeal Lymphoma in a Child – Case Report and Review of Literature
title_sort laryngeal lymphoma in a child – case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709388/
https://www.ncbi.nlm.nih.gov/pubmed/36474489
http://dx.doi.org/10.22038/IJORL.2022.57663.2984
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