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Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery
INTRODUCTION: Few studies evaluated the treatment of postoperative pain in middle ear surgery. MATERIALS AND METHODS: We conducted a randomized clinical trial to evaluate the efficacy of dexamethasone in the management of postoperative pain in middle ear surgery. Group G1 received an intravenous inj...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709389/ https://www.ncbi.nlm.nih.gov/pubmed/36474493 http://dx.doi.org/10.22038/IJORL.2022.60292.3077 |
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author | Zouche, Imen Abdelmalak, Feris Triki, Zied Ketata, Salma Sellami, Moncef Karoui, Abdelhamid |
author_facet | Zouche, Imen Abdelmalak, Feris Triki, Zied Ketata, Salma Sellami, Moncef Karoui, Abdelhamid |
author_sort | Zouche, Imen |
collection | PubMed |
description | INTRODUCTION: Few studies evaluated the treatment of postoperative pain in middle ear surgery. MATERIALS AND METHODS: We conducted a randomized clinical trial to evaluate the efficacy of dexamethasone in the management of postoperative pain in middle ear surgery. Group G1 received an intravenous injection of 2 ml of physiological saline 30 minutes before the end of the procedure. Group G2 received a 2 ml intravenous solution containing 8 mg of dexamethasone, 30 minutes before the end of the procedure. Pain perception was measured by the Visual analog scale (VAS) every 10 min during the first hour and then every 6 hours during the 24 hours postoperatively. The delay of the first analgesic demand and the consumption of analgesics use during the first 24 hours postoperatively, were recorded. RESULTS: VAS values were lower in G2at all measurement points during the first hour, as well as the first 24h postoperatively (Mann-Whitney test, P<0.05).The delay of the analgesic request was (0 (0-60) for G1 versus 0 (0-80) for G2, P=0.04, Mann-Whitney test). Morphine was used in 44% of the patients in G1 against 19% for G2 (P = 0.031). There was a significant difference between G1 and G2 in terms of the total dose of morphine consumed (P= 0.028, Mann-Whitney test). Paracetamol demand was lower in group 2 at all points of assessment during the first 24 hours postoperatively. CONCLUSIONS: Intravenous dexamethasone is effective in decreasing pain and analgesic requirement, during the first 24 hours postoperatively, in patients undergoing middle ear surgery. |
format | Online Article Text |
id | pubmed-9709389 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-97093892022-12-05 Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery Zouche, Imen Abdelmalak, Feris Triki, Zied Ketata, Salma Sellami, Moncef Karoui, Abdelhamid Iran J Otorhinolaryngol Original Article INTRODUCTION: Few studies evaluated the treatment of postoperative pain in middle ear surgery. MATERIALS AND METHODS: We conducted a randomized clinical trial to evaluate the efficacy of dexamethasone in the management of postoperative pain in middle ear surgery. Group G1 received an intravenous injection of 2 ml of physiological saline 30 minutes before the end of the procedure. Group G2 received a 2 ml intravenous solution containing 8 mg of dexamethasone, 30 minutes before the end of the procedure. Pain perception was measured by the Visual analog scale (VAS) every 10 min during the first hour and then every 6 hours during the 24 hours postoperatively. The delay of the first analgesic demand and the consumption of analgesics use during the first 24 hours postoperatively, were recorded. RESULTS: VAS values were lower in G2at all measurement points during the first hour, as well as the first 24h postoperatively (Mann-Whitney test, P<0.05).The delay of the analgesic request was (0 (0-60) for G1 versus 0 (0-80) for G2, P=0.04, Mann-Whitney test). Morphine was used in 44% of the patients in G1 against 19% for G2 (P = 0.031). There was a significant difference between G1 and G2 in terms of the total dose of morphine consumed (P= 0.028, Mann-Whitney test). Paracetamol demand was lower in group 2 at all points of assessment during the first 24 hours postoperatively. CONCLUSIONS: Intravenous dexamethasone is effective in decreasing pain and analgesic requirement, during the first 24 hours postoperatively, in patients undergoing middle ear surgery. Mashhad University of Medical Sciences 2022-11 /pmc/articles/PMC9709389/ /pubmed/36474493 http://dx.doi.org/10.22038/IJORL.2022.60292.3077 Text en https://creativecommons.org/licenses/by/3.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/ (https://creativecommons.org/licenses/by/3.0/) ) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Zouche, Imen Abdelmalak, Feris Triki, Zied Ketata, Salma Sellami, Moncef Karoui, Abdelhamid Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery |
title | Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery |
title_full | Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery |
title_fullStr | Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery |
title_full_unstemmed | Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery |
title_short | Intravenous Dexamethasone Reduces Pain in Middle Ear Surgery |
title_sort | intravenous dexamethasone reduces pain in middle ear surgery |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709389/ https://www.ncbi.nlm.nih.gov/pubmed/36474493 http://dx.doi.org/10.22038/IJORL.2022.60292.3077 |
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