Cross-reactivity between histone demethylase inhibitor valproic acid and DNA methylation in glioblastoma cell lines

Currently, valproic acid (VPA) is known as an inhibitor of histone deacetylase (epigenetic drug) and is used for the clinical treatment of epileptic events in the course of glioblastoma multiforme (GBM). Which improves the clinical outcome of those patients. We analyzed the level of 5-methylcytosine...

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Detalles Bibliográficos
Autores principales: Barciszewska, Anna-Maria, Belter, Agnieszka, Gawrońska, Iwona, Giel-Pietraszuk, Małgorzata, Naskręt-Barciszewska, Mirosława Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709419/
https://www.ncbi.nlm.nih.gov/pubmed/36465345
http://dx.doi.org/10.3389/fonc.2022.1033035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709419/
https://www.ncbi.nlm.nih.gov/pubmed/36465345
http://dx.doi.org/10.3389/fonc.2022.1033035

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