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Cross-reactivity between histone demethylase inhibitor valproic acid and DNA methylation in glioblastoma cell lines
Currently, valproic acid (VPA) is known as an inhibitor of histone deacetylase (epigenetic drug) and is used for the clinical treatment of epileptic events in the course of glioblastoma multiforme (GBM). Which improves the clinical outcome of those patients. We analyzed the level of 5-methylcytosine...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709419/ https://www.ncbi.nlm.nih.gov/pubmed/36465345 http://dx.doi.org/10.3389/fonc.2022.1033035 |