The inhibition of NCS-1 binding to Ric8a rescues fragile X syndrome mice model phenotypes

Fragile X syndrome (FXS) is caused by the loss of function of Fragile X mental retardation protein (FMRP). FXS is one of the leading monogenic causes of intellectual disability (ID) and autism. Although it is caused by the failure of a single gene, FMRP that functions as an RNA binding protein affec...

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Detalles Bibliográficos
Autores principales: Cogram, Patricia, Fernández-Beltrán, Luis C., Casarejos, María José, Sánchez-Yepes, Sonia, Rodríguez-Martín, Eulalia, García-Rubia, Alfonso, Sánchez-Barrena, María José, Gil, Carmen, Martínez, Ana, Mansilla, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709425/
https://www.ncbi.nlm.nih.gov/pubmed/36466176
http://dx.doi.org/10.3389/fnins.2022.1007531

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