Hyperinsulinemia-induced microglial mitochondrial dynamic and metabolic alterations lead to neuroinflammation in vivo and in vitro

Numerous studies have demonstrated that type 2 diabetes (T2D) is closely linked to the occurrence of Alzheimer’s disease (AD). Nevertheless, the underlying mechanisms for this association are still unknown. Insulin resistance (IR) hallmarked by hyperinsulinemia, as the earliest and longest-lasting p...

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Detalles Bibliográficos
Autores principales: Yang, Xiaohan, Xu, Yuan, Gao, Wenting, Wang, Li, Zhao, Xinnan, Liu, Gang, Fan, Kai, Liu, Shuang, Hao, Huimin, Qu, Siyan, Dong, Renhou, Ma, Xiaokai, Ma, Jianmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709447/
https://www.ncbi.nlm.nih.gov/pubmed/36466168
http://dx.doi.org/10.3389/fnins.2022.1036872

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