Cargando…

Mitochondrial antioxidant SkQ1 decreases inflammation following hemorrhagic shock by protecting myocardial mitochondria

Background: Hemorrhagic shock (HS) is a type of hypovolemic shock characterized by hemodynamic instability, tissue hypoperfusion and cellular hypoxia. In pathophysiology, the gradual accumulation of reactive oxygen species (ROS) damages the mitochondria, leading to irreversible cell damage and the r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Bo, Ye, Jingjing, Gan, Lebin, Li, Rui, Zhang, Mengwei, Sun, Diya, Weng, Lin, Xiong, Yufei, Xu, Jun, Zhang, Peng, Huang, Wei, Zheng, Ming, Wang, Tianbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709459/ https://www.ncbi.nlm.nih.gov/pubmed/36467681 http://dx.doi.org/10.3389/fphys.2022.1047909

Ejemplares similares

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents
por: Anisimov, Vladimir N., et al.
Publicado: (2011)

The Analgesic Effect of the Mitochondria-Targeted Antioxidant SkQ1 in Pancreatic Inflammation
por: Weniger, Maximilian, et al.
Publicado: (2016)

Mitochondria-targeted antioxidant SkQ1 inhibits leukotriene synthesis in human neutrophils
por: Sud’ina, Galina F., et al.
Publicado: (2022)

Mitochondria-Targeted Antioxidant SkQ1 Prevents Anesthesia-Induced Dry Eye Syndrome
por: Zernii, Evgeni Yu., et al.
Publicado: (2017)

Therapeutic Effect of the Mitochondria-Targeted Antioxidant SkQ1 on the Culture Model of Multiple Sclerosis
por: Fetisova, Elena K., et al.
Publicado: (2019)

The mitochondria-targeted antioxidant SkQ1 but not N-acetylcysteine reverses aging-related biomarkers in rats
por: Kolosova, Nataliya G., et al.
Publicado: (2012)

Mitochondria-targeted antioxidant SkQ1 improves impaired dermal wound healing in old mice
por: Demyanenko, Ilya A., et al.
Publicado: (2015)

Mitochondria-targeted antioxidant SkQ1 reduces age-related alterations in the ultrastructure of the lacrimal gland
por: Bakeeva, Lora E., et al.
Publicado: (2016)

Mitochondria-Targeted Antioxidant SkQ1 Improves Dermal Wound Healing in Genetically Diabetic Mice
por: Demyanenko, Ilya A., et al.
Publicado: (2017)

Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats
por: Obukhova, Lidia A., et al.
Publicado: (2009)

Mitochondrion-targeted antioxidant SkQ1 prevents rapid animal death caused by highly diverse shocks
por: Skulachev, V. P., et al.
Publicado: (2023)

Antioxidant SkQ1 delays sarcopenia-associated damage of mitochondrial ultrastructure
por: Vays, Valeriya B., et al.
Publicado: (2014)

Suppression of AMD-Like Pathology by Mitochondria-Targeted Antioxidant SkQ1 Is Associated with a Decrease in the Accumulation of Amyloid β and in mTOR Activity
por: Muraleva, Natalia A., et al.
Publicado: (2019)

Suppression of Alzheimer's Disease-Like Pathology Progression by Mitochondria-Targeted Antioxidant SkQ1: A Transcriptome Profiling Study
por: Stefanova, Natalia A., et al.
Publicado: (2019)

Mitochondria-Targeted Antioxidant SkQ1 Prevents the Development of Experimental Colitis in Mice and Impairment of the Barrier Function of the Intestinal Epithelium
por: Fedorov, Artem V., et al.
Publicado: (2022)

Therapeutic Action of the Mitochondria-Targeted Antioxidant SkQ1 on Retinopathy in OXYS Rats Linked with Improvement of VEGF and PEDF Gene Expression
por: Markovets, Anton M., et al.
Publicado: (2011)

Changes in Glial Support of the Hippocampus during the Development of an Alzheimer’s Disease-like Pathology and Their Correction by Mitochondria-Targeted Antioxidant SkQ1
por: Rudnitskaya, Ekaterina A., et al.
Publicado: (2022)

SkQ1 treatment and food restriction — two ways to retard an aging program of organisms
por: Skulachev, Vladimir P.
Publicado: (2011)

Treating Neurodegenerative Disease with Antioxidants: Efficacy of the Bioactive Phenol Resveratrol and Mitochondrial-Targeted MitoQ and SkQ
por: Shinn, Lindsey J., et al.
Publicado: (2021)

The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy
por: Perepechaeva, M. L., et al.
Publicado: (2014)

Mitochondria-Targeted Antioxidants SkQ1 and MitoTEMPO Failed to Exert a Long-Term Beneficial Effect in Murine Polymicrobial Sepsis
por: Rademann, Pia, et al.
Publicado: (2017)

Efficacy of Mitochondrial Antioxidant Plastoquinonyl-decyl-triphenylphosphonium Bromide (SkQ1) in the Rat Model of Autoimmune Arthritis
por: Andreev-Andrievskiy, Alexander A., et al.
Publicado: (2016)

Improved health-span and lifespan in mtDNA mutator mice treated with the mitochondrially targeted antioxidant SkQ1
por: Shabalina, Irina G., et al.
Publicado: (2017)

SkQ1 Suppresses the p38 MAPK Signaling Pathway Involved in Alzheimer’s Disease-Like Pathology in OXYS Rats
por: Muraleva, Natalia A., et al.
Publicado: (2020)

Genetic Variability of the AcrAB-TolC Multidrug Efflux Pump Underlies SkQ1 Resistance in Gram-Negative Bacteria
por: Nazarov, P. A., et al.
Publicado: (2019)

The role of mtDAMPs in the trauma-induced systemic inflammatory response syndrome
por: Ye, Jingjing, et al.
Publicado: (2023)

Mitochondrial Antioxidant SkQ1 Has a Beneficial Effect in Experimental Diabetes as Based on the Analysis of Expression of microRNAs and mRNAs for the Oxidative Metabolism Regulators
por: Dvoretskaya, Yuliya, et al.
Publicado: (2021)

Mitochondria and Coenzyme Q10 in the Pathogenesis of Preeclampsia
por: Teran, Enrique, et al.
Publicado: (2018)

SkQ1 Ophthalmic Solution for Dry Eye Treatment: Results of a Phase 2 Safety and Efficacy Clinical Study in the Environment and During Challenge in the Controlled Adverse Environment Model
por: Petrov, Anton, et al.
Publicado: (2016)

Mitochondria-targeted antioxidant SKQ1 protects cornea from oxidative damage induced by ultraviolet irradiation and mechanical injury
por: Zernii, Evgeni Yu., et al.
Publicado: (2018)

Mitochondrial Targeted Antioxidant SKQ1 Ameliorates Acute Kidney Injury by Inhibiting Ferroptosis
por: Song, Jiayu, et al.
Publicado: (2022)

The protective effect of pericytes on vascular permeability after hemorrhagic shock and their relationship with Cx43
por: He, Shuangshuang, et al.
Publicado: (2022)

Danger signals in traumatic hemorrhagic shock and new lines for clinical applications
por: Dufour-Gaume, Frédérique, et al.
Publicado: (2023)

Toward Biological Pacing by Cellular Delivery of Hcn2/SkM1
por: Végh, Anna M. D., et al.
Publicado: (2021)

Characteristics and Risk Factors of Myocardial Injury after Traumatic Hemorrhagic Shock
por: Zhao, Xiujuan, et al.
Publicado: (2022)

The Role of SKQ1 (Visomitin) in Inflammation and Wound Healing of the Ocular Surface
por: Wei, Yi, et al.
Publicado: (2018)

Ophiopogonin A Alleviates Hemorrhagic Shock-Induced Renal Injury via Induction of Nrf2 Expression
por: Sheng, Xiaoming, et al.
Publicado: (2021)

Class of hemorrhagic shock is associated with progressive diastolic coronary flow reversal and diminished left ventricular function
por: Elansary, Noha N., et al.
Publicado: (2022)

N-Acetyl-L-Cysteine Protects Organ Function After Hemorrhagic Shock Combined With Seawater Immersion in Rats by Correcting Coagulopathy and Acidosis
por: Liu, Yiyan, et al.
Publicado: (2022)

From Bioblasts to Mitochondria: Ever Expanding Roles of Mitochondria in Cell Physiology
por: O'Rourke, Brian
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ottn3bh2qa01keqadvar0c0099