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Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages

Acute kidney injury (AKI) is a common clinical syndrome with complex pathogenesis, characterized by a rapid decline in kidney function in the short term. Worse still, the incomplete recovery from AKI increases the risk of progression to chronic kidney disease (CKD). However, the pathogenesis and und...

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Detalles Bibliográficos
Autores principales:	Guan, Xu, Liu, Yong, Xin, Wang, Qin, Shaozong, Gong, Shuiqin, Xiao, Tangli, Zhang, Daohai, Li, Yan, Xiong, Jiachuan, Yang, Ke, He, Ting, Zhao, Jinghong, Huang, Yinghui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709464/ https://www.ncbi.nlm.nih.gov/pubmed/36467025 http://dx.doi.org/10.3389/fphar.2022.1030800

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