Cargando…
Ratiometric imaging of minor groove binders in mammalian cells using Raman microscopy
Quantitative drug imaging in live cells is a major challenge in drug discovery and development. Many drug screening techniques are performed in solution, and therefore do not consider the impact of the complex cellular environment in their result. As such, important features of drug–cell interaction...
Autores principales: | Tentellino, Christian, Tipping, William J., McGee, Leah M. C., Bain, Laura M., Wetherill, Corinna, Laing, Stacey, Tyson-Hirst, Izaak, Suckling, Colin J., Beveridge, Rebecca, Scott, Fraser J., Faulds, Karen, Graham, Duncan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709774/ https://www.ncbi.nlm.nih.gov/pubmed/36544571 http://dx.doi.org/10.1039/d2cb00159d |
Ejemplares similares
-
Ratiometric Raman imaging reveals the new anti-cancer potential of lipid targeting drugs
por: Jamieson, Lauren E., et al.
Publicado: (2018) -
Selective Anti-Leishmanial Strathclyde Minor Groove Binders Using an N-Oxide Tail-Group Modification
por: Perieteanu, Marina C., et al.
Publicado: (2022) -
Determination
of Intracellular Esterase Activity Using
Ratiometric Raman Sensing and Spectral Phasor Analysis
por: Braddick, Henry J., et al.
Publicado: (2023) -
Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders
por: Kennedy, Alan R., et al.
Publicado: (2017) -
Stimulated Raman scattering microscopy with spectral phasor analysis: applications in assessing drug–cell interactions
por: Tipping, William J., et al.
Publicado: (2022)