Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 Spike protein

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SARS-CoV-2 is a novel coronavirus responsible for the COVID-19 pandemic. Its high pathogenicity is due to SARS-CoV-2 spike protein (S protein) contacting host-cell receptors. A critical hallmark of COVID-19 is the occurrence of coagulopathies. Here, we report the direct observation of the interactio...

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Detalles Bibliográficos
Autores principales: Kuhn, Christopher Cyrus, Basnet, Nirakar, Bodakuntla, Satish, Alvarez-Brecht, Pelayo, Nichols, Scott, Martinez-Sanchez, Antonio, Agostini, Lorenzo, Soh, Young-Min, Takagi, Junichi, Biertümpfel, Christian, Mizuno, Naoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9709796/
https://www.ncbi.nlm.nih.gov/pubmed/36451880
http://dx.doi.org/10.1101/2022.11.22.517574
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