Novel trehalose-based excipients for stabilizing nebulized anti-SARS-CoV-2 antibody

COVID-19 is caused by the infection of the lungs by SARS-CoV-2. Monoclonal antibodies, such as sotrovimab, showed great efficiency in neutralizing the virus before its internalization by lung epithelial cells. However, parenteral routes are still the preferred route of administration, even for local...

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Detalles Bibliográficos
Autores principales: Noverraz, François, Robin, Baptiste, Passemard, Solène, Fauvel, Bénédicte, Presumey, Jessy, Rigal, Emilie, Cookson, Alan, Chopineau, Joël, Martineau, Pierre, Villalba, Martin, Jorgensen, Christian, Aubert-Pouëssel, Anne, Morille, Marie, Gerber-Lemaire, Sandrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710110/
https://www.ncbi.nlm.nih.gov/pubmed/36462738
http://dx.doi.org/10.1016/j.ijpharm.2022.122463

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