A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant

INTRODUCTION: This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant. METHODS: We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant. RESULTS: The Delta-variant...

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Detalles Bibliográficos
Autores principales: Li, Yanzi, Wang, Zhi, Liu, Junhui, Han, Jianfeng, Yang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710252/
https://www.ncbi.nlm.nih.gov/pubmed/36457976
http://dx.doi.org/10.5114/aoms/155114
Descripción
Sumario:INTRODUCTION: This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant. METHODS: We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant. RESULTS: The Delta-variant group showed a higher infection rate in minors, who had higher incidence of anosmia or dysgeusia and shorter incubation period. Unvaccinated patients had a 15.59-fold higher risk of severe classification than vaccinated patients. The viral clearance time was significantly shorter in the Delta-variant group. CONCLUSIONS: The Delta-variant group show higher transmissibility, and vaccination reduces the incidence of severe classification and promotes viral clearance.

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