A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant

INTRODUCTION: This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant. METHODS: We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant. RESULTS: The Delta-variant...

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Autores principales: Li, Yanzi, Wang, Zhi, Liu, Junhui, Han, Jianfeng, Yang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710252/
https://www.ncbi.nlm.nih.gov/pubmed/36457976
http://dx.doi.org/10.5114/aoms/155114
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author Li, Yanzi
Wang, Zhi
Liu, Junhui
Han, Jianfeng
Yang, Lin
author_facet Li, Yanzi
Wang, Zhi
Liu, Junhui
Han, Jianfeng
Yang, Lin
author_sort Li, Yanzi
collection PubMed
description INTRODUCTION: This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant. METHODS: We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant. RESULTS: The Delta-variant group showed a higher infection rate in minors, who had higher incidence of anosmia or dysgeusia and shorter incubation period. Unvaccinated patients had a 15.59-fold higher risk of severe classification than vaccinated patients. The viral clearance time was significantly shorter in the Delta-variant group. CONCLUSIONS: The Delta-variant group show higher transmissibility, and vaccination reduces the incidence of severe classification and promotes viral clearance.
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spelling pubmed-97102522022-11-30 A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant Li, Yanzi Wang, Zhi Liu, Junhui Han, Jianfeng Yang, Lin Arch Med Sci Research Letter INTRODUCTION: This study aimed to investigate the clinical features and vaccine effectiveness of patients with the SARS-CoV-2 wild-type strain and the Delta variant. METHODS: We retrospectively evaluated patients with the SARS-CoV-2 wild-type strain and the Delta variant. RESULTS: The Delta-variant group showed a higher infection rate in minors, who had higher incidence of anosmia or dysgeusia and shorter incubation period. Unvaccinated patients had a 15.59-fold higher risk of severe classification than vaccinated patients. The viral clearance time was significantly shorter in the Delta-variant group. CONCLUSIONS: The Delta-variant group show higher transmissibility, and vaccination reduces the incidence of severe classification and promotes viral clearance. Termedia Publishing House 2022-11-07 /pmc/articles/PMC9710252/ /pubmed/36457976 http://dx.doi.org/10.5114/aoms/155114 Text en Copyright: © 2022 Termedia & Banach https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Research Letter
Li, Yanzi
Wang, Zhi
Liu, Junhui
Han, Jianfeng
Yang, Lin
A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant
title A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant
title_full A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant
title_fullStr A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant
title_full_unstemmed A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant
title_short A comparison of the protective effect of vaccination and clinical features between the SARS-CoV-2 wild-type strain and Delta (B.1.617.2) variant
title_sort comparison of the protective effect of vaccination and clinical features between the sars-cov-2 wild-type strain and delta (b.1.617.2) variant
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710252/
https://www.ncbi.nlm.nih.gov/pubmed/36457976
http://dx.doi.org/10.5114/aoms/155114
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