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MiRNA-21 promotes differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells by regulating the Ajuba/Isl1 axis pathway

INTRODUCTION: In this study, we aimed to investigate the role of miRNA-21 and the regulating pathway that promotes the differentiation of bone marrow mesenchymal stem cells (BMSCs). METHODS: We used miR-21-OE, miR-21-KD, ajuba-OE and ajuba-KD plasmids to infect BMSCs. The expression of miRNA-21, aju...

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Detalles Bibliográficos
Autores principales: Yang, Wengang, Zhao, Lei, Xue, Song, Liu, Jidong, Shan, Jianggui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710289/
https://www.ncbi.nlm.nih.gov/pubmed/36457985
http://dx.doi.org/10.5114/aoms/154956

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