PSICalc: a novel approach to identifying and ranking critical non-proximal interdependencies within the overall protein structure

MOTIVATION: AlphaFold has been a major advance in predicting protein structure, but still leaves the problem of determining which sub-molecular components of a protein are essential for it to carry out its function within the cell. Direct coupling analysis predicts two- and three-amino acid contacts...

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Detalles Bibliográficos
Autores principales: Townsley, Thomas D, Wilson, James T, Akers, Harrison, Bryant, Timothy, Cordova, Salvador, Wallace, T L, Durston, Kirk K, Deweese, Joseph E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710643/
https://www.ncbi.nlm.nih.gov/pubmed/36699404
http://dx.doi.org/10.1093/bioadv/vbac058

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