Cargando…

Left atrial appendage morphology with the progression of atrial fibrillation

Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transes...

Descripción completa

Detalles Bibliográficos
Autores principales: Takaya, Yoichi, Nakayama, Rie, Yokohama, Fumi, Toh, Norihisa, Nakagawa, Koji, Miyamoto, Masakazu, Ito, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710751/
https://www.ncbi.nlm.nih.gov/pubmed/36449497
http://dx.doi.org/10.1371/journal.pone.0278172
_version_ 1784841432386764800
author Takaya, Yoichi
Nakayama, Rie
Yokohama, Fumi
Toh, Norihisa
Nakagawa, Koji
Miyamoto, Masakazu
Ito, Hiroshi
author_facet Takaya, Yoichi
Nakayama, Rie
Yokohama, Fumi
Toh, Norihisa
Nakagawa, Koji
Miyamoto, Masakazu
Ito, Hiroshi
author_sort Takaya, Yoichi
collection PubMed
description Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transesophageal echocardiography (TEE) were included. Patients were classified into non-AF (n = 64), paroxysmal AF (n = 86), persistent AF (n = 87), or long-standing persistent AF (n = 62). LAA morphology, including LAA ostial diameter and depth, was assessed using TEE. Patients with long-standing persistent AF had larger LAA ostial diameter and depth and lower LAA flow velocity. The maximum LAA ostial diameter was 19 ± 4 mm in patients with non-AF, 21 ± 4 mm in patients with paroxysmal AF, 23 ± 5 mm in patients with persistent AF, and 26 ± 5 mm in patients with long-standing persistent AF. LAA ostial diameter was increased by 2 or 3 mm with the progression of AF. LAA ostial diameter was correlated with LA volume index (R = 0.37, P < 0.01) and the duration of continuous AF (R = 0.30, P < 0.01), but not with age or the period from the onset of AF. In conclusion, LAA size was increased with the progression of AF.
format Online
Article
Text
id pubmed-9710751
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-97107512022-12-01 Left atrial appendage morphology with the progression of atrial fibrillation Takaya, Yoichi Nakayama, Rie Yokohama, Fumi Toh, Norihisa Nakagawa, Koji Miyamoto, Masakazu Ito, Hiroshi PLoS One Research Article Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transesophageal echocardiography (TEE) were included. Patients were classified into non-AF (n = 64), paroxysmal AF (n = 86), persistent AF (n = 87), or long-standing persistent AF (n = 62). LAA morphology, including LAA ostial diameter and depth, was assessed using TEE. Patients with long-standing persistent AF had larger LAA ostial diameter and depth and lower LAA flow velocity. The maximum LAA ostial diameter was 19 ± 4 mm in patients with non-AF, 21 ± 4 mm in patients with paroxysmal AF, 23 ± 5 mm in patients with persistent AF, and 26 ± 5 mm in patients with long-standing persistent AF. LAA ostial diameter was increased by 2 or 3 mm with the progression of AF. LAA ostial diameter was correlated with LA volume index (R = 0.37, P < 0.01) and the duration of continuous AF (R = 0.30, P < 0.01), but not with age or the period from the onset of AF. In conclusion, LAA size was increased with the progression of AF. Public Library of Science 2022-11-30 /pmc/articles/PMC9710751/ /pubmed/36449497 http://dx.doi.org/10.1371/journal.pone.0278172 Text en © 2022 Takaya et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Takaya, Yoichi
Nakayama, Rie
Yokohama, Fumi
Toh, Norihisa
Nakagawa, Koji
Miyamoto, Masakazu
Ito, Hiroshi
Left atrial appendage morphology with the progression of atrial fibrillation
title Left atrial appendage morphology with the progression of atrial fibrillation
title_full Left atrial appendage morphology with the progression of atrial fibrillation
title_fullStr Left atrial appendage morphology with the progression of atrial fibrillation
title_full_unstemmed Left atrial appendage morphology with the progression of atrial fibrillation
title_short Left atrial appendage morphology with the progression of atrial fibrillation
title_sort left atrial appendage morphology with the progression of atrial fibrillation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710751/
https://www.ncbi.nlm.nih.gov/pubmed/36449497
http://dx.doi.org/10.1371/journal.pone.0278172
work_keys_str_mv AT takayayoichi leftatrialappendagemorphologywiththeprogressionofatrialfibrillation
AT nakayamarie leftatrialappendagemorphologywiththeprogressionofatrialfibrillation
AT yokohamafumi leftatrialappendagemorphologywiththeprogressionofatrialfibrillation
AT tohnorihisa leftatrialappendagemorphologywiththeprogressionofatrialfibrillation
AT nakagawakoji leftatrialappendagemorphologywiththeprogressionofatrialfibrillation
AT miyamotomasakazu leftatrialappendagemorphologywiththeprogressionofatrialfibrillation
AT itohiroshi leftatrialappendagemorphologywiththeprogressionofatrialfibrillation