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Left atrial appendage morphology with the progression of atrial fibrillation
Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transes...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710751/ https://www.ncbi.nlm.nih.gov/pubmed/36449497 http://dx.doi.org/10.1371/journal.pone.0278172 |
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author | Takaya, Yoichi Nakayama, Rie Yokohama, Fumi Toh, Norihisa Nakagawa, Koji Miyamoto, Masakazu Ito, Hiroshi |
author_facet | Takaya, Yoichi Nakayama, Rie Yokohama, Fumi Toh, Norihisa Nakagawa, Koji Miyamoto, Masakazu Ito, Hiroshi |
author_sort | Takaya, Yoichi |
collection | PubMed |
description | Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transesophageal echocardiography (TEE) were included. Patients were classified into non-AF (n = 64), paroxysmal AF (n = 86), persistent AF (n = 87), or long-standing persistent AF (n = 62). LAA morphology, including LAA ostial diameter and depth, was assessed using TEE. Patients with long-standing persistent AF had larger LAA ostial diameter and depth and lower LAA flow velocity. The maximum LAA ostial diameter was 19 ± 4 mm in patients with non-AF, 21 ± 4 mm in patients with paroxysmal AF, 23 ± 5 mm in patients with persistent AF, and 26 ± 5 mm in patients with long-standing persistent AF. LAA ostial diameter was increased by 2 or 3 mm with the progression of AF. LAA ostial diameter was correlated with LA volume index (R = 0.37, P < 0.01) and the duration of continuous AF (R = 0.30, P < 0.01), but not with age or the period from the onset of AF. In conclusion, LAA size was increased with the progression of AF. |
format | Online Article Text |
id | pubmed-9710751 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-97107512022-12-01 Left atrial appendage morphology with the progression of atrial fibrillation Takaya, Yoichi Nakayama, Rie Yokohama, Fumi Toh, Norihisa Nakagawa, Koji Miyamoto, Masakazu Ito, Hiroshi PLoS One Research Article Left atrial appendage (LAA) size is crucial for determining the indication of transcatheter LAA closure. The aim of this study was to evaluate the differences in LAA morphology according to the types of atrial fibrillation (AF). A total of 299 patients (mean age: 67 ± 13 years) who underwent transesophageal echocardiography (TEE) were included. Patients were classified into non-AF (n = 64), paroxysmal AF (n = 86), persistent AF (n = 87), or long-standing persistent AF (n = 62). LAA morphology, including LAA ostial diameter and depth, was assessed using TEE. Patients with long-standing persistent AF had larger LAA ostial diameter and depth and lower LAA flow velocity. The maximum LAA ostial diameter was 19 ± 4 mm in patients with non-AF, 21 ± 4 mm in patients with paroxysmal AF, 23 ± 5 mm in patients with persistent AF, and 26 ± 5 mm in patients with long-standing persistent AF. LAA ostial diameter was increased by 2 or 3 mm with the progression of AF. LAA ostial diameter was correlated with LA volume index (R = 0.37, P < 0.01) and the duration of continuous AF (R = 0.30, P < 0.01), but not with age or the period from the onset of AF. In conclusion, LAA size was increased with the progression of AF. Public Library of Science 2022-11-30 /pmc/articles/PMC9710751/ /pubmed/36449497 http://dx.doi.org/10.1371/journal.pone.0278172 Text en © 2022 Takaya et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Takaya, Yoichi Nakayama, Rie Yokohama, Fumi Toh, Norihisa Nakagawa, Koji Miyamoto, Masakazu Ito, Hiroshi Left atrial appendage morphology with the progression of atrial fibrillation |
title | Left atrial appendage morphology with the progression of atrial fibrillation |
title_full | Left atrial appendage morphology with the progression of atrial fibrillation |
title_fullStr | Left atrial appendage morphology with the progression of atrial fibrillation |
title_full_unstemmed | Left atrial appendage morphology with the progression of atrial fibrillation |
title_short | Left atrial appendage morphology with the progression of atrial fibrillation |
title_sort | left atrial appendage morphology with the progression of atrial fibrillation |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710751/ https://www.ncbi.nlm.nih.gov/pubmed/36449497 http://dx.doi.org/10.1371/journal.pone.0278172 |
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