The SARS-CoV-2 spike protein binds and modulates estrogen receptors

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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein binds angiotensin-converting enzyme 2 as its primary infection mechanism. Interactions between S and endogenous proteins occur after infection but are not well understood. We profiled binding of S against >9000 hum...

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Detalles Bibliográficos
Autores principales: Solis, Oscar, Beccari, Andrea R., Iaconis, Daniela, Talarico, Carmine, Ruiz-Bedoya, Camilo A., Nwachukwu, Jerome C., Cimini, Annamaria, Castelli, Vanessa, Bertini, Riccardo, Montopoli, Monica, Cocetta, Veronica, Borocci, Stefano, Prandi, Ingrid G., Flavahan, Kelly, Bahr, Melissa, Napiorkowski, Anna, Chillemi, Giovanni, Ooka, Masato, Yang, Xiaoping, Zhang, Shiliang, Xia, Menghang, Zheng, Wei, Bonaventura, Jordi, Pomper, Martin G., Hooper, Jody E., Morales, Marisela, Rosenberg, Avi Z., Nettles, Kendall W., Jain, Sanjay K., Allegretti, Marcello, Michaelides, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710872/
https://www.ncbi.nlm.nih.gov/pubmed/36449624
http://dx.doi.org/10.1126/sciadv.add4150

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