The long noncoding RNA FEDORA is a cell type– and sex-specific regulator of depression

Women suffer from depression at twice the rate of men, but the underlying molecular mechanisms are poorly understood. Here, we identify marked baseline sex differences in the expression of long noncoding RNAs (lncRNAs), a class of regulatory transcripts, in human postmortem brain tissue that are pro...

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Detalles Bibliográficos
Autores principales: Issler, Orna, van der Zee, Yentl Y., Ramakrishnan, Aarthi, Xia, Sunhui, Zinsmaier, Alexander K., Tan, Chunfeng, Li, Wei, Browne, Caleb J., Walker, Deena M., Salery, Marine, Torres-Berrío, Angélica, Futamura, Rita, Duffy, Julia E., Labonte, Benoit, Girgenti, Matthew J., Tamminga, Carol A., Dupree, Jeffrey L., Dong, Yan, Murrough, James W., Shen, Li, Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9710883/
https://www.ncbi.nlm.nih.gov/pubmed/36449610
http://dx.doi.org/10.1126/sciadv.abn9494

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