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Decoupling dedifferentiation and G(2)/M arrest in kidney fibrosis

Understanding the cellular mechanisms underlying chronic kidney disease (CKD) progression is required to develop effective therapeutic approaches. In this issue of the JCI, Taguchi, Elias, et al. explore the relationship between cyclin G1 (CG1), an atypical cyclin that induces G(2)/M proximal tubule...

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Detalles Bibliográficos
Autor principal: Humphreys, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711866/
https://www.ncbi.nlm.nih.gov/pubmed/36453550
http://dx.doi.org/10.1172/JCI163846