Cargando…

Decoupling dedifferentiation and G(2)/M arrest in kidney fibrosis

Understanding the cellular mechanisms underlying chronic kidney disease (CKD) progression is required to develop effective therapeutic approaches. In this issue of the JCI, Taguchi, Elias, et al. explore the relationship between cyclin G1 (CG1), an atypical cyclin that induces G(2)/M proximal tubule...

Descripción completa

Detalles Bibliográficos
Autor principal:	Humphreys, Benjamin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711866/ https://www.ncbi.nlm.nih.gov/pubmed/36453550 http://dx.doi.org/10.1172/JCI163846

Ejemplares similares

β-cell dedifferentiation in diabetes is important, but what is it?
por: Weir, Gordon C, et al.
Publicado: (2013)

Dedifferentiation rescues senescence of progeria cells but only while pluripotent
por: Niedernhofer, Laura J, et al.
Publicado: (2011)

Decoupling Arrest Origins in Hydrogels of Cellulose Nanofibrils
por: Xu, Hua-Neng, et al.
Publicado: (2018)

HDAC9-mediated epithelial cell cycle arrest in G2/M contributes to kidney fibrosis in male mice
por: Zhang, Yang, et al.
Publicado: (2023)

Hypothermia and cardiac arrest: the promise of intra-arrest cooling
por: Band, Roger A, et al.
Publicado: (2008)

The political economy and dynamics of bifurcated world governance and the decoupling of value chains: An alternative perspective
por: Vertinsky, Ilan, et al.
Publicado: (2023)

Cellular origin of cancer: dedifferentiation or stem cell maturation arrest?
por: Sell, S
Publicado: (1993)

Decoupling in international business: The ‘new’ vulnerability of globalization and MNEs’ response strategies
por: Cui, Victor, et al.
Publicado: (2023)

Role of Akt1 in renal fibrosis and tubular dedifferentiation during the progression of acute kidney injury to chronic kidney disease
por: Kim, Il Young, et al.
Publicado: (2021)

Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation
por: Taguchi, Kensei, et al.
Publicado: (2022)

mTOR favors senescence over quiescence in p53-arrested cells
por: Schug, Thaddeus T.
Publicado: (2010)

Numb contributes to renal fibrosis by promoting tubular epithelial cell cycle arrest at G2/M
por: Zhu, Fengxin, et al.
Publicado: (2016)

Not so WEE: Targeting G(2)/M to kill mesothelioma cells
por: Dent, Paul
Publicado: (2014)

Retroperitoneal dedifferentiated liposarcoma with osteosarcomatous dedifferentiation
por: Nguyen, Vinh N., et al.
Publicado: (2015)

Dietary NiCl(2) causes G(2)/M cell cycle arrest in the broiler's kidney
por: Guo, Hongrui, et al.
Publicado: (2015)

Repeated Administration of Cisplatin Transforms Kidney Fibroblasts through G2/M Arrest and Cellular Senescence
por: Yu, Jia-Bin, et al.
Publicado: (2022)

β-Arrestin2 arrests the clearance of tau in FTLD
por: Thathiah, Amantha
Publicado: (2020)

BMPER Ameliorates Renal Fibrosis by Inhibiting Tubular Dedifferentiation and Fibroblast Activation
por: Xie, Ting, et al.
Publicado: (2021)

Aberrant DNA repair as a potential contributor for the clonal evolution in subsets of anaplastic thyroid carcinomas arising through dedifferentiation: implications for future therapeutic algorithms?
por: Juhlin, Carl Christofer
Publicado: (2020)

Decoupling of evolutionary changes in mRNA and protein levels
por: Jiang, Daohan, et al.
Publicado: (2023)

On the Decoupling of Evolutionary Changes in mRNA and Protein Levels
por: Jiang, Daohan, et al.
Publicado: (2023)

Arresting metastasis within the microcirculation
por: Varotsos Vrynas, Angelos, et al.
Publicado: (2021)

Dedifferentiated solitary fibrous tumor of the kidney: A case report
por: Izumi, Keita, et al.
Publicado: (2022)

Dedifferentiated liposarcoma of the left kidney: A rare case report
por: Li, Chiao-Ching, et al.
Publicado: (2018)

Targeted temperature management and cardiac arrest after the TTM-2 study
por: Taccone, Fabio Silvio, et al.
Publicado: (2021)

Mass dedifferentiation
por: LeBrasseur, Nicole
Publicado: (2004)

Epithelial Signaling through the RUNX1/AKT Pathway: A New Therapeutic Target in Kidney Fibrosis
por: Galichon, Pierre
Publicado: (2018)

Myogenic dedifferentiation is associated with poor outcomes in retroperitoneal dedifferentiated liposarcomas
por: Dorian Yarih, Garcia-Ortega, et al.
Publicado: (2021)

Neurological prognostication after cardiac arrest
por: Friberg, Hans
Publicado: (2008)

Decoupling Drupal: a decoupled design approach for web applications
por: Mayekar, Deepali
Publicado: (2017)

Dedifferentiation of esophageal progenitors in metaplasia and cancer
por: Vercauteren Drubbel, Alizée, et al.
Publicado: (2021)

Compact Wideband Self-Decoupled MIMO Antenna for 5G Communications
por: Li, Qian, et al.
Publicado: (2022)

MIMO 5G Smartphone Antenna with Tri-Band and Decoupled Elements
por: Hou, Jianqiang, et al.
Publicado: (2023)

Determination of $\alpha _s(m_Z)$ by the non-perturbative decoupling method
por: Dalla Brida, Mattia, et al.
Publicado: (2022)

p53 upregulated by HIF-1α promotes hypoxia-induced G2/M arrest and renal fibrosis in vitro and in vivo
por: Liu, Limin, et al.
Publicado: (2018)

G2/M cell cycle arrest in the life cycle of viruses
por: Davy, Clare, et al.
Publicado: (2007)

Optimizing neurologic prognosis after cardiac arrest
por: Tirschwell, David
Publicado: (2006)

Improved cardiac arrest outcomes: as time goes by?
por: Morley, Peter T
Publicado: (2007)

Cardiac arrest - has the time of MRI come?
por: Galanaud, Damien, et al.
Publicado: (2010)

Prehospital cooling in cardiac arrest - the next frontier?
por: Søreide, Eldar
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_bdrqqpbdg0bmhdj74tfgl0dn0l