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Is androgen receptor activity in metastatic prostate cancer a good biomarker for bipolar androgen therapy?
Androgen deprivation therapy (ADT) is the longstanding treatment for advanced prostate cancer (PC) because androgen receptor (AR) is the key therapeutic vulnerability for this disease. Bipolar androgen therapy (BAT) — the rapid cycling of supraphysiologic androgen (SPA) and low serum testosterone le...
Autores principales: | Peinetti, Nahuel, Bilusic, Marijo, Burnstein, Kerry L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711867/ https://www.ncbi.nlm.nih.gov/pubmed/36453547 http://dx.doi.org/10.1172/JCI165357 |
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