IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis

Platelets and megakaryocytes are critical players in immune responses. Recent reports suggest infection and inflammation alter the megakaryocyte and platelet transcriptome to induce altered platelet reactivity. We determined whether nonviral sepsis induces differential platelet gene expression and r...

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Detalles Bibliográficos
Autores principales: Campbell, Robert A., Manne, Bhanu Kanth, Banerjee, Meenakshi, Middleton, Elizabeth A., Ajanel, Abigail, Schwertz, Hansjorg, Denorme, Frederik, Stubben, Chris, Montenont, Emilie, Saperstein, Samantha, Page, Lauren, Tolley, Neal D., Lim, Diana L., Brown, Samuel M., Grissom, Colin K., Sborov, Douglas W., Krishnan, Anandi, Rondina, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711880/
https://www.ncbi.nlm.nih.gov/pubmed/36194487
http://dx.doi.org/10.1172/JCI153014

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