Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report

A case of autoimmune hepatitis (AIH) following COVID-19 vaccination in a very old patient is presented. An 85-year-old woman who had preexisting Sjögren’s syndrome (SS) but had never shown evidence of liver disease was admitted to our hospital due to jaundice and liver dysfunction. Further laborator...

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Detalles Bibliográficos
Autores principales: Yoshida, Yukinari, Iwata, Norikazu, Ishii, Yoshifumi, Hinoda, Yuji, Endo, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Allergy/Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711889/
https://www.ncbi.nlm.nih.gov/pubmed/36465723
http://dx.doi.org/10.7759/cureus.30896
Descripción
Sumario:A case of autoimmune hepatitis (AIH) following COVID-19 vaccination in a very old patient is presented. An 85-year-old woman who had preexisting Sjögren’s syndrome (SS) but had never shown evidence of liver disease was admitted to our hospital due to jaundice and liver dysfunction. Further laboratory tests, imaging studies, and liver histology proved this to be a case of definite AIH. Eight weeks before the disease onset, she had received the second dose of mRNA COVID-19 vaccination. To our knowledge, this is the first case of AIH following COVID-19 vaccination in a patient with a history of SS.

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