Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report

A case of autoimmune hepatitis (AIH) following COVID-19 vaccination in a very old patient is presented. An 85-year-old woman who had preexisting Sjögren’s syndrome (SS) but had never shown evidence of liver disease was admitted to our hospital due to jaundice and liver dysfunction. Further laborator...

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Autores principales: Yoshida, Yukinari, Iwata, Norikazu, Ishii, Yoshifumi, Hinoda, Yuji, Endo, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Allergy/Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711889/
https://www.ncbi.nlm.nih.gov/pubmed/36465723
http://dx.doi.org/10.7759/cureus.30896
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author Yoshida, Yukinari
Iwata, Norikazu
Ishii, Yoshifumi
Hinoda, Yuji
Endo, Takao
author_facet Yoshida, Yukinari
Iwata, Norikazu
Ishii, Yoshifumi
Hinoda, Yuji
Endo, Takao
author_sort Yoshida, Yukinari
collection PubMed
description A case of autoimmune hepatitis (AIH) following COVID-19 vaccination in a very old patient is presented. An 85-year-old woman who had preexisting Sjögren’s syndrome (SS) but had never shown evidence of liver disease was admitted to our hospital due to jaundice and liver dysfunction. Further laboratory tests, imaging studies, and liver histology proved this to be a case of definite AIH. Eight weeks before the disease onset, she had received the second dose of mRNA COVID-19 vaccination. To our knowledge, this is the first case of AIH following COVID-19 vaccination in a patient with a history of SS.
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spelling pubmed-97118892022-12-02 Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report Yoshida, Yukinari Iwata, Norikazu Ishii, Yoshifumi Hinoda, Yuji Endo, Takao Cureus Allergy/Immunology A case of autoimmune hepatitis (AIH) following COVID-19 vaccination in a very old patient is presented. An 85-year-old woman who had preexisting Sjögren’s syndrome (SS) but had never shown evidence of liver disease was admitted to our hospital due to jaundice and liver dysfunction. Further laboratory tests, imaging studies, and liver histology proved this to be a case of definite AIH. Eight weeks before the disease onset, she had received the second dose of mRNA COVID-19 vaccination. To our knowledge, this is the first case of AIH following COVID-19 vaccination in a patient with a history of SS. Cureus 2022-10-31 /pmc/articles/PMC9711889/ /pubmed/36465723 http://dx.doi.org/10.7759/cureus.30896 Text en Copyright © 2022, Yoshida et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Allergy/Immunology
Yoshida, Yukinari
Iwata, Norikazu
Ishii, Yoshifumi
Hinoda, Yuji
Endo, Takao
Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report
title Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report
title_full Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report
title_fullStr Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report
title_full_unstemmed Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report
title_short Autoimmune Hepatitis Following mRNA COVID-19 Vaccination in a Very Old Patient With Preexisting Sjögren’s Syndrome: A Case Report
title_sort autoimmune hepatitis following mrna covid-19 vaccination in a very old patient with preexisting sjögren’s syndrome: a case report
topic Allergy/Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711889/
https://www.ncbi.nlm.nih.gov/pubmed/36465723
http://dx.doi.org/10.7759/cureus.30896
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