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Partial Molar Pregnancy With Normal Karyotype

Partial molar pregnancy results from fertilization of a haploid ovum by two sperms or duplication of one sperm, resulting in a triploid karyotype. The coexistence of partial mole with normal fetus karyotype is rare and occurs in 0.005-0.01% of all pregnancies. It is considered a challenging diagnosi...

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Detalles Bibliográficos
Autores principales: Al Ghadeer, Hussain A, Al Kishi, Nihad, Algurini, Kholoud H, Albesher, Ahlam B, AlGhadeer, Mohammed R, Alsalman, Ayat A, Bubshait, Aisha A, Alkishi, Bassil M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711909/
https://www.ncbi.nlm.nih.gov/pubmed/36465796
http://dx.doi.org/10.7759/cureus.30934
Descripción
Sumario:Partial molar pregnancy results from fertilization of a haploid ovum by two sperms or duplication of one sperm, resulting in a triploid karyotype. The coexistence of partial mole with normal fetus karyotype is rare and occurs in 0.005-0.01% of all pregnancies. It is considered a challenging diagnosis. Here, we report a case of a 38-year-old primigravida diagnosed indecently at 16 weeks of gestation. She was on regular antenatal care and had partial molar pregnancy with a female fetus with diploid karyotype and no apparent malformation. This pregnancy ended with intrauterine fetal death. Histological examination of the placenta showed partial hydatidiform mole changes.