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Partial Molar Pregnancy With Normal Karyotype
Partial molar pregnancy results from fertilization of a haploid ovum by two sperms or duplication of one sperm, resulting in a triploid karyotype. The coexistence of partial mole with normal fetus karyotype is rare and occurs in 0.005-0.01% of all pregnancies. It is considered a challenging diagnosi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711909/ https://www.ncbi.nlm.nih.gov/pubmed/36465796 http://dx.doi.org/10.7759/cureus.30934 |
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author | Al Ghadeer, Hussain A Al Kishi, Nihad Algurini, Kholoud H Albesher, Ahlam B AlGhadeer, Mohammed R Alsalman, Ayat A Bubshait, Aisha A Alkishi, Bassil M |
author_facet | Al Ghadeer, Hussain A Al Kishi, Nihad Algurini, Kholoud H Albesher, Ahlam B AlGhadeer, Mohammed R Alsalman, Ayat A Bubshait, Aisha A Alkishi, Bassil M |
author_sort | Al Ghadeer, Hussain A |
collection | PubMed |
description | Partial molar pregnancy results from fertilization of a haploid ovum by two sperms or duplication of one sperm, resulting in a triploid karyotype. The coexistence of partial mole with normal fetus karyotype is rare and occurs in 0.005-0.01% of all pregnancies. It is considered a challenging diagnosis. Here, we report a case of a 38-year-old primigravida diagnosed indecently at 16 weeks of gestation. She was on regular antenatal care and had partial molar pregnancy with a female fetus with diploid karyotype and no apparent malformation. This pregnancy ended with intrauterine fetal death. Histological examination of the placenta showed partial hydatidiform mole changes. |
format | Online Article Text |
id | pubmed-9711909 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-97119092022-12-02 Partial Molar Pregnancy With Normal Karyotype Al Ghadeer, Hussain A Al Kishi, Nihad Algurini, Kholoud H Albesher, Ahlam B AlGhadeer, Mohammed R Alsalman, Ayat A Bubshait, Aisha A Alkishi, Bassil M Cureus Genetics Partial molar pregnancy results from fertilization of a haploid ovum by two sperms or duplication of one sperm, resulting in a triploid karyotype. The coexistence of partial mole with normal fetus karyotype is rare and occurs in 0.005-0.01% of all pregnancies. It is considered a challenging diagnosis. Here, we report a case of a 38-year-old primigravida diagnosed indecently at 16 weeks of gestation. She was on regular antenatal care and had partial molar pregnancy with a female fetus with diploid karyotype and no apparent malformation. This pregnancy ended with intrauterine fetal death. Histological examination of the placenta showed partial hydatidiform mole changes. Cureus 2022-10-31 /pmc/articles/PMC9711909/ /pubmed/36465796 http://dx.doi.org/10.7759/cureus.30934 Text en Copyright © 2022, Al Ghadeer et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Genetics Al Ghadeer, Hussain A Al Kishi, Nihad Algurini, Kholoud H Albesher, Ahlam B AlGhadeer, Mohammed R Alsalman, Ayat A Bubshait, Aisha A Alkishi, Bassil M Partial Molar Pregnancy With Normal Karyotype |
title | Partial Molar Pregnancy With Normal Karyotype |
title_full | Partial Molar Pregnancy With Normal Karyotype |
title_fullStr | Partial Molar Pregnancy With Normal Karyotype |
title_full_unstemmed | Partial Molar Pregnancy With Normal Karyotype |
title_short | Partial Molar Pregnancy With Normal Karyotype |
title_sort | partial molar pregnancy with normal karyotype |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711909/ https://www.ncbi.nlm.nih.gov/pubmed/36465796 http://dx.doi.org/10.7759/cureus.30934 |
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