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Isoschaftoside Inhibits Lipopolysaccharide-Induced Inflammation in Microglia through Regulation of HIF-1α-Mediated Metabolic Reprogramming

Isoschaftoside is a C-glycosyl flavonoid extracted from the root exudates of Desmodium uncinatum and Abrus cantoniensis. Previous studies suggested that C-glycosyl flavonoid has neuroprotective effects with the property of reducing oxidative stress and inflammatory markers. Microglia are key cellula...

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Detalles Bibliográficos
Autores principales: Guan, Shuyuan, Sun, Lingbin, Wang, Xihua, Huang, Xirui, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711954/
https://www.ncbi.nlm.nih.gov/pubmed/36467557
http://dx.doi.org/10.1155/2022/5227335