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Paeoniflorin Inhibits LPS-Induced Activation of Splenic CD4(+) T Lymphocytes and Relieves Pathological Symptoms in MRL/lpr Mice by Suppressing IRAK1 Signaling
Interleukin-1receptor-associated kinase 1 (IRAK1) plays a critical role in systemic lupus erythematosus (SLE). It was reported that SLE was associated with an inflammatory response mediated by defective immune tolerance, including overproduction of autoantibodies, chronic inflammation, and organ dam...
Autores principales: | Ji, Lina, Wang, Shenglong, Wu, Shan, Bao, Jie, Xie, Guanqun, Zhang, Yan, Xu, Liping, Lin, Na, Wang, Jian, Fan, Yongsheng, Fu, Danqing, Dai, Qiaoding |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711961/ https://www.ncbi.nlm.nih.gov/pubmed/36467552 http://dx.doi.org/10.1155/2022/5161890 |
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