Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler

Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia,...

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Autores principales: Searcy, Kristie, Jagadish, Apoorva, Pichilingue-Reto, Patricia, Baliga, Radhakrishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711990/
https://www.ncbi.nlm.nih.gov/pubmed/36466432
http://dx.doi.org/10.1155/2022/3811170
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author Searcy, Kristie
Jagadish, Apoorva
Pichilingue-Reto, Patricia
Baliga, Radhakrishna
author_facet Searcy, Kristie
Jagadish, Apoorva
Pichilingue-Reto, Patricia
Baliga, Radhakrishna
author_sort Searcy, Kristie
collection PubMed
description Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia, and end organ damage. This is present in severe cases of COVID-19 and in hemolytic uremic syndrome (HUS) commonly caused by Escherichia coli (E.coli) 0157:H7. We report a novel case of a toddler who presented with classic features suggestive of HUS characterized by bloody diarrhea followed by thrombocytopenia, hemolytic anemia, and acute kidney injury, in whom a polymerase chain reaction (PCR) test for SARS-CoV-2 was positive.
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spelling pubmed-97119902022-12-01 Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler Searcy, Kristie Jagadish, Apoorva Pichilingue-Reto, Patricia Baliga, Radhakrishna Case Rep Pediatr Case Report Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world. Thrombotic microangiopathy (TMA) is a triad of hemolytic anemia, thrombocytopenia, and end organ damage. This is present in severe cases of COVID-19 and in hemolytic uremic syndrome (HUS) commonly caused by Escherichia coli (E.coli) 0157:H7. We report a novel case of a toddler who presented with classic features suggestive of HUS characterized by bloody diarrhea followed by thrombocytopenia, hemolytic anemia, and acute kidney injury, in whom a polymerase chain reaction (PCR) test for SARS-CoV-2 was positive. Hindawi 2022-11-23 /pmc/articles/PMC9711990/ /pubmed/36466432 http://dx.doi.org/10.1155/2022/3811170 Text en Copyright © 2022 Kristie Searcy et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Searcy, Kristie
Jagadish, Apoorva
Pichilingue-Reto, Patricia
Baliga, Radhakrishna
Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_full Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_fullStr Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_full_unstemmed Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_short Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
title_sort coronavirus disease 2019 (covid-19) associated hemolytic uremic syndrome in a toddler
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9711990/
https://www.ncbi.nlm.nih.gov/pubmed/36466432
http://dx.doi.org/10.1155/2022/3811170
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