Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages have escaped most receptor-binding domain (RBD)-targeting therapeutic neutralizing antibodies (NAbs), which proves that previous NAb drug screening strategies are deficient against the fast-evolving SARS-CoV-2. Better b...

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Detalles Bibliográficos
Autores principales: Cao, Yunlong, Jian, Fanchong, Zhang, Zhiying, Yisimayi, Ayijiang, Hao, Xiaohua, Bao, Linlin, Yuan, Fei, Yu, Yuanling, Du, Shuo, Wang, Jing, Xiao, Tianhe, Song, Weiliang, Zhang, Ying, Liu, Pulan, An, Ran, Wang, Peng, Wang, Yao, Yang, Sijie, Niu, Xiao, Zhang, Yuhang, Gu, Qingqing, Shao, Fei, Hu, Yaling, Yin, Weidong, Zheng, Aihua, Wang, Youchun, Qin, Chuan, Jin, Ronghua, Xiao, Junyu, Xie, Xiaoliang Sunney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712074/
https://www.ncbi.nlm.nih.gov/pubmed/36493787
http://dx.doi.org/10.1016/j.celrep.2022.111845

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