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Central nervous system involvement in childhood acute lymphoblastic leukemia: challenges and solutions

Delivery of effective anti-leukemic agents to the central nervous system (CNS) is considered essential for cure of childhood acute lymphoblastic leukemia. Current CNS-directed therapy comprises systemic therapy with good CNS-penetration accompanied by repeated intrathecal treatments up to 26 times o...

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Detalles Bibliográficos
Autores principales:	Thastrup, Maria, Duguid, Alasdair, Mirian, Christian, Schmiegelow, Kjeld, Halsey, Christina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712093/ https://www.ncbi.nlm.nih.gov/pubmed/36266325 http://dx.doi.org/10.1038/s41375-022-01714-x

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