JAK/BCL2 inhibition acts synergistically with LSD1 inhibitors to selectively target ETP-ALL

ETP-ALL (Early T cell Progenitor Acute Lymphoblastic Leukemia) represents a high-risk subtype of T cell acute lymphocytic leukemia (T-ALL). Therapeutically, ETP-ALL patients frequently relapse after conventional chemotherapy highlighting the need for alternative therapeutic approaches. Using our ZEB...

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Detalles Bibliográficos
Autores principales: Benyoucef, Aissa, Haigh, Katharina, Cuddihy, Andrew, Haigh, Jody J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712096/
https://www.ncbi.nlm.nih.gov/pubmed/36229595
http://dx.doi.org/10.1038/s41375-022-01716-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712096/
https://www.ncbi.nlm.nih.gov/pubmed/36229595
http://dx.doi.org/10.1038/s41375-022-01716-9

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