Medin co-aggregates with vascular amyloid-β in Alzheimer’s disease

Aggregates of medin amyloid (a fragment of the protein MFG-E8, also known as lactadherin) are found in the vasculature of almost all humans over 50 years of age(1,2), making it the most common amyloid currently known. We recently reported that medin also aggregates in blood vessels of ageing wild-ty...

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Detalles Bibliográficos
Autores principales: Wagner, Jessica, Degenhardt, Karoline, Veit, Marleen, Louros, Nikolaos, Konstantoulea, Katerina, Skodras, Angelos, Wild, Katleen, Liu, Ping, Obermüller, Ulrike, Bansal, Vikas, Dalmia, Anupriya, Häsler, Lisa M., Lambert, Marius, De Vleeschouwer, Matthias, Davies, Hannah A., Madine, Jillian, Kronenberg-Versteeg, Deborah, Feederle, Regina, Del Turco, Domenico, Nilsson, K. Peter R., Lashley, Tammaryn, Deller, Thomas, Gearing, Marla, Walker, Lary C., Heutink, Peter, Rousseau, Frederic, Schymkowitz, Joost, Jucker, Mathias, Neher, Jonas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9712113/
https://www.ncbi.nlm.nih.gov/pubmed/36385530
http://dx.doi.org/10.1038/s41586-022-05440-3

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